Browse by University and Academic Department

A

AL Shaaili, Nada (2022) Characterisation of stromal gene expression in soft tissue sarcoma. PhD thesis, University of Sheffield.

Alandejani, Faisal Abdulwahab A (2022) Assessing the Severity and Prognosis in PAH Using Magnetic Resonance Imaging and NT-proBNP. PhD thesis, University of Sheffield.

Albalawi, Fahad (2022) ROLE OF AUTOIMMUNE REGULATOR (AIRE) IN THE PATHOGENESIS OF NEUROLOGICAL DISORDERS ASSOCIATED WITH AUTOIMMUNE POLYGLANDULAR SYNDROME TYPE 1. PhD thesis, University of Sheffield.

Alharbi, Zeyad (2022) Towards the development of a tractable model to study innate immune responses of the respiratory tract to Staphylococcus aureus infection. PhD thesis, University of Sheffield.

Alkhoshaiban, Abdulaziz (2022) Towards defining an antiviral role for BPIFB1 in the airway epithelium. PhD thesis, University of Sheffield.

Almansouri, Taghreed (2022) HYPOXIA-MEDIATED CHANGES IN THE MICROGLIAL PHENOTYPE OF AGE-ASSOCIATED WHITE MATTER LESIONS AND A ZEBRAFISH MODEL. PhD thesis, University of Sheffield.

Alotaibi, Majed Mutlaq A ORCID: https://orcid.org/0000-0002-3721-7110 (2022) The Role of Olfactory Dysfunction and Cognitive Decline Observed in the Ageing Population, MCI and AD. PhD thesis, University of Sheffield.

Alshehre, Sallwa ORCID: https://orcid.org/0000-0001-7078-3053 (2022) Effect of endometriosis on oocyte quantity and quality of patients undergoing In vitro fertilisation (IVF)/ Intracytoplasmic sperm injection (ICSI). PhD thesis, University of Sheffield.

Alzahrani, Hyfa (2022) Breast cancer extracellular vesicles transfer viral cargo following oncolytic virotherapy. PhD thesis, University of Sheffield.

Arredondo, Hector ORCID: https://orcid.org/0000-0003-3214-0123 (2022) Defining the role of exercise in prostate cancer bone metastasis. PhD thesis, University of Sheffield.

Ashford, Bridget ORCID: https://orcid.org/0000-0002-9247-3125 (2022) Characterisation of the Neuroinflammatory Response in Human Sporadic Motor Neuron Disease. PhD thesis, University of Sheffield.

Astley, Joshua ORCID: https://orcid.org/0000-0002-6552-5436 (2022) The role of deep learning in structural and functional lung imaging. PhD thesis, University of Sheffield.

Aydin, Veli Kaan (2022) The bone microenvironment as a therapeutic target in breast cancer bone metastasis. PhD thesis, University of Sheffield.

B

Bacila, Irina-Alexandra (2022) Understanding the Metabolic Problems in Patients with Congenital Adrenal Hyperplasia. PhD thesis, University of Sheffield.

Barnes, Katy Amanda (2022) Understanding the Mechanisms Leading to Mitochondrial Abnormalities in Alzheimer's Disease. PhD thesis, University of Sheffield.

Binti Liaqat Ali Khan, Norhayati ORCID: https://orcid.org/0000-0001-7781-0552 (2022) Embryo-maternal communication: extracellular vesicles role in mediating trophoblast-endometrial interactions. PhD thesis, University of Sheffield.

Brooks, Alenka ORCID: https://orcid.org/0000-0001-7162-7845 (2022) Young people with Inflammatory Bowel Disease: the relationship with their disease, identity, and illness perceptions and healthcare at a time of transition. PhD thesis, University of Sheffield.

Brudenell, Emma (2022) Structure-function studies on 5′ nucleases. PhD thesis, University of Sheffield.

C

Cañedo, Jaime Obguia ORCID: https://orcid.org/0000-0002-2612-4357 (2022) The ultrastructural features of the surface of macrophages and the mechanics of phagocytosis. PhD thesis, University of Sheffield.

Chalakova, Zhaklin ORCID: https://orcid.org/0009-0007-3971-2020 (2022) Development and characterisation of a zebrafish larval model to investigate mechanisms for pathophysiology of intracranial hypertension in cryptococcal meningitis. PhD thesis, University of Sheffield.

Chittock, John ORCID: https://orcid.org/0000-0002-1595-7441 (2022) Investigating biomarkers of skin barrier development and breakdown associated with early-onset atopic dermatitis. PhD thesis, University of Sheffield.

Chowdhury, Md Miraj Kobad (2022) Towards defining roles for PIERCE1 and C15ORF65 in multiciliated cells through gene editing. PhD thesis, University of Sheffield.

D

Dowey, Rebecca (2022) Examining neutrophil function in acute and chronic inflammation to identify novel therapeutic strategies to treat disease. PhD thesis, University of Sheffield.

Dowling, Lisa ORCID: https://orcid.org/0000-0002-8332-358X (2022) Dynapenic Abdominal Obesity – Falls, Fractures, Muscle Function, and miRNA Profile. PhD thesis, University of Sheffield.

E

Eissa, Mohammad Rahman ORCID: https://orcid.org/0000-0002-5584-5815 (2022) Translational technology in type 1 diabetes to help optimise glycaemic control and sustain behaviour change. PhD thesis, University of Sheffield.

Elwazir, Aya ORCID: https://orcid.org/0000-0002-2766-3854 (2022) The role of the circular RNA circANRIL16-5 in atherosclerosis. PhD thesis, University of Sheffield.

Errington, Niamh ORCID: https://orcid.org/0000-0001-6768-7394 (2022) Machine learning approaches for uncovering miRNAs as biomarkers of Pulmonary Hypertension. PhD thesis, University of Sheffield.

F

Fargher, Emma May ORCID: https://orcid.org/0000-0003-3626-5927 (2022) Using zebrafish to assess the role of inflammation-linked Parkinson’s disease risk genes in neurodegeneration. PhD thesis, University of Sheffield.

Fields, Leona (2022) Targeting the Fanconi anaemia pathway in neuroblastoma. PhD thesis, University of Sheffield.

G

Gaines, Stuart William ORCID: https://orcid.org/0000-0002-8220-2647 (2022) Tails of twists and turns: Using zebrafish to unravel neutrophil chromatin remodelling. PhD thesis, University of Sheffield.

George, Christopher ORCID: https://orcid.org/0000-0001-6335-4760 (2022) Defining the differential effects of Zoledronic acid under pre and post-menopausal concentrations of oestradiol on anti-cancer immunity. PhD thesis, University of Sheffield.

Graves, Emily (2022) Investigating the Role of the RNA Exporter Protein Gle1 in Spinal Muscular Atrophy. PhD thesis, University of Sheffield.

Gullapudi, Venkata Rukmini Latha (2022) Characterising haemodynamic responses to Conventional Haemodialysis. M.D. thesis, University of Sheffield.

H

Haley, Arfah (Hazel) (2022) The potential role of computed blood flow in the management of patients with acute coronary syndrome (ACS). M.D. thesis, University of Sheffield.

Hammond, Ffion (2022) Targeting host-derived signalling to activate leukocytes and improve infection outcomes in zebrafish models. PhD thesis, University of Sheffield.

Handforth, Catherine (2022) Prostate cancer and bone health. PhD thesis, University of Sheffield.

Hardman, Simon (2022) Prophylactic azithromycin in protracted bacterial bronchitis: parental experience and impact on bacterial resistance and the microbiome. M.D. thesis, University of Sheffield.

Herman, Kimberly Dana ORCID: https://orcid.org/0000-0002-8672-0599 (2022) ErbB inhibitors as a potential future treatment for chronic obstructive pulmonary disease. PhD thesis, University of Sheffield.

Hillary, Sarah Louise (2022) Post-Surgical Hypoparathyroidism (PoSH): Causes, consequences and novel preventative techniques. PhD thesis, University of Sheffield.

Hughes, Rachel Mary (2022) Uncovering the mechanism of action of a novel therapeutic compound for the treatment of Parkinson's disease. PhD thesis, University of Sheffield.

Hull, Rebecca (2022) The Influence of Antibiotics, Hypoxia and Neutrophil Proteins on the Evolution of Antibiotic Resistance in Staphylococcus aureus. PhD thesis, University of Sheffield.

K

Kariotis, Sokratis ORCID: https://orcid.org/0000-0001-9993-6017 (2022) Unsupervised machine learning of high dimensional data for patient stratification. PhD thesis, University of Sheffield.

Keerie, Amy Francesca Amanda ORCID: https://orcid.org/0000-0001-9389-3802 (2022) Evaluation of M102 as a novel therapeutic in Amyotrophic Lateral Sclerosis (ALS). PhD thesis, University of Sheffield.

Kok, Jannigje ORCID: https://orcid.org/0000-0001-7185-1329 (2022) Astrocyte-induced DNA damage as a mechanism of motor neuron death in amyotrophic lateral sclerosis. PhD thesis, University of Sheffield.

L

Landeros de la Isla, Arturo ORCID: https://orcid.org/0009-0006-8795-9637 (2022) DNA replication inhibitor as a potential antimicrobial agent targeting neglected tropical pathogens. PhD thesis, University of Sheffield.

M

MIDDLETON, JENNIFER (2022) Early, remote evaluation of therapeutic efficacy and disease worsening in patients with pulmonary arterial hypertension. PhD thesis, University of Sheffield.

Madrigal Esquivel, Claudia ORCID: https://orcid.org/0000-0002-0051-1017 (2022) VEGFA isoform expression and its regulation of the Tumour Microenvironment in Soft Tissue Sarcoma. PhD thesis, University of Sheffield.

Marchi, Paolo ORCID: https://orcid.org/0000-0002-8893-3790 (2022) A comparison between C9ORF72-derived poly-GA DPRs at different stages of protein aggregation in neurons and glia. PhD thesis, University of Sheffield.

Matuszyk, Martyna (2022) Characterising the astrocyte responses to oligomeric and fibrillary Aβ1-42 in Alzheimer's disease. PhD thesis, University of Sheffield.

McKenzie, Joanne (2022) Membrane microdomains as therapeutic targets to control respiratory syncytial virus. PhD thesis, University of Sheffield.

Moyle, Bethany (2022) Remote ischaemic conditioning for fatigue after stroke (RICFAST): a pilot, single-blind, randomised, placebo-controlled trial. PhD thesis, University of Sheffield.

N

Nelson, Thomas Andrew ORCID: https://orcid.org/0000-0002-8930-6342 (2022) Fibrin clot properties in patients with atrial fibrillation: associations with clinical characteristics, biomarkers, and clinical outcomes. PhD thesis, University of Sheffield.

O

Ogola, Thomas Oludhe (2022) The bone microenvironment as a master regulator of disseminated tumour cells responsible for breast cancer recurrence. PhD thesis, University of Sheffield.

P

Payne, Thomas ORCID: https://orcid.org/0000-0001-6753-7847 (2022) Mitochondrial dysfunction as a therapeutic target in Parkinson's Disease. PhD thesis, University of Sheffield.

R

Ren, Jie (2022) PROTECTIVE MECHANISM OF SIRT1 ON SUBVENTRICULAR ZONE DERIVED NEURAL STEM CELLS DURING AGING IN MICE. PhD thesis, University of Sheffield.

Richards, Jeremy (2022) Investigating the impact of Zoledronate on the healthspan of mice. PhD thesis, University of Sheffield.

S

Samuelson, Clare (2022) Optimising Techniques for CRISPR/Cas9 Genome Editing as Treatment for Haemoglobinopathies. PhD thesis, University of Sheffield.

Snodgrass, Ryan Oliver ORCID: https://orcid.org/0000-0002-9131-9193 (2022) Investigating the roles of endoglin in cardiovascular development, disease and repair. PhD thesis, University of Sheffield.

T

Teo, Mario Kempes Chee Hseong ORCID: https://orcid.org/0000-0002-0051-3303 (2022) MOYAMOYA DISEASE IN THE WESTERN POPULATION AFTER EXTRACRANIAL-INTRACRANIAL BYPASS AND DEVELOPMENT OF PREDICTIVE MODELLING FOR PERIOPERATIVE STROKE RISK. PhD thesis, University of Sheffield.

U

Urwin, Lucy ORCID: https://orcid.org/0000-0002-7667-8630 (2022) The development of in vitro corneal infection models for antimicrobial drug testing. PhD thesis, University of Sheffield.

V

Venneri, Annalena ORCID: https://orcid.org/0000-0002-9488-2301 (2022) Early and differential diagnosis of Alzheimer's disease. M.D. thesis, University of Sheffield.

W

Walter, Melanie ORCID: https://orcid.org/0000-0003-3241-522X (2022) Exploitation of the UDP-glucose hydrolase NUDT22 as novel target in cancer therapy. PhD thesis, University of Sheffield.

Z

Zhou, Ziqi ORCID: https://orcid.org/0000-0001-6401-2797 (2022) Endothelial responses to shear stress differs in healthy aortas and atherosclerotic plaques. PhD thesis, University of Sheffield.