Browse by University and Academic Department

A

Agapiou, Michaela ORCID: https://orcid.org/0000-0002-0703-5324 (2021) Dissecting the RNA-binding activity and function of HOW(S) during Drosophila melanogaster spermatogenesis. PhD thesis, University of Leeds.

Al-Rhoom Al-Hajaya, Yousef Hamad M ORCID: https://orcid.org/0000-0002-9282-671X (2021) Plant catalases: New insights into targeting and activity. PhD thesis, University of Leeds.

Alsulaimani, Fayez Fahad F (2021) Use of Affimers for Targeting S. aureus Biofilms. PhD thesis, University of Leeds.

Arter, Christopher James (2021) Fragment-based Discovery of Modulators of the Aurora-A Kinase. PhD thesis, University of Leeds.

B

Billenness, Gregory John (2021) SH2 domain-binding Affimer Reagents as tools to investigate cell signalling pathways. PhD thesis, University of Leeds.

Branch, Jessie ORCID: https://orcid.org/0000-0002-2687-1301 (2021) The study of Cellvibrio japonicus X-domains as potential LPMO redox partners. PhD thesis, University of Leeds.

Brighton, Katie Louise (2021) Understanding the role and regulation of PTEN in Adenovirus 5 infection. MSc by research thesis, University of Leeds.

Brown, Madeleine ORCID: https://orcid.org/0000-0003-1672-4401 (2021) Analysis of the effect of Aβ fibril polymorphism on toxicity, degradation and activation of an inflammatory response. PhD thesis, University of Leeds.

C

Carden, Holli (2021) Targeting host cell ion channels to treat herpesvirus infections. PhD thesis, University of Leeds.

Cawthorne, Eleanor (2021) Investigation of novel receptor tyrosine kinase mediated non-canonical signalling in breast cancer. PhD thesis, University of Leeds.

Chau, Chi Cheng ORCID: https://orcid.org/0000-0002-3134-6798 (2021) Single Molecule Delivery and Detection into Crowded Environment with a Solid-State Nanopore. PhD thesis, University of Leeds.

D

Debski-Antoniak, Oliver James (2021) Influenza a virus: Investigation of novel therapeutic treatments and underlying mechanisms. PhD thesis, University of Leeds.

Dickens, Stuart Mark ORCID: https://orcid.org/0000-0002-5357-1072 (2021) Establishing the perineuronal net as a neuroprotective barrier in Parkinson’s disease. PhD thesis, University of Leeds.

E

Ebo, Jessica Sarah ORCID: https://orcid.org/0000-0002-5684-4355 (2021) Selection and evolution of aggregation resistant proteins. PhD thesis, University of Leeds.

F

Fazal, Asif ORCID: https://orcid.org/0000-0002-7293-9725 (2021) Characterising and engineering enzymes involved in antimycin and surugamide biosynthesis. PhD thesis, University of Leeds.

G

Galarion, Luiza Hidalgo (2021) Towards a renaissance in antibiotic discovery: New sources, new tools. PhD thesis, University of Leeds.

Good, Sarah Catherine (2021) Amyloid Disease Models in C. elegans: insights into the toxicity of B2-microglobulin and islet amyloid polypeptide. PhD thesis, University of Leeds.

Guo, Jinchao (2021) Enhancement of alphavirus replication in mammalian cells at sub-physiological temperatures. PhD thesis, University of Leeds.

H

Harvey, Maia Elizabeth ORCID: https://orcid.org/0000-0002-2413-5730 (2021) Developing a toolkit of assays to assess protein-protein interactions. PhD thesis, University of Leeds.

Henderson, James George ORCID: https://orcid.org/0000-0002-0709-5124 (2021) Towards the Structures of the Parathyroid Hormone Receptors. PhD thesis, University of Leeds.

Holt, Marcus John Edward ORCID: https://orcid.org/0000-0002-5116-879X (2021) The role of the autosomal recessive primary microcephaly protein ASPM: A protein involved in mitosis. PhD thesis, University of Leeds.

Hoste, Alexis Claude Raymond ORCID: https://orcid.org/0000-0001-6724-6062 (2021) Development of diagnostics methods for new emerging viruses. PhD thesis, University of Leeds.

J

Jones, Christopher Mark ORCID: https://orcid.org/0000-0002-4513-4964 (2021) The Cellular Response to Microenvironmental Stress in Barrett’s Oesophagus. PhD thesis, University of Leeds.

K

Kamiński, Tomasz Piotr ORCID: https://orcid.org/0000-0003-4823-3797 (2021) Immunofluorescent imaging in live cells. PhD thesis, University of Leeds.

L

Lowen, Dominic (2021) The role of HDAC9 in JAK2V617F-driven myeloproliferative neoplasms. PhD thesis, University of Leeds.

M

Manners, Oliver William ORCID: https://orcid.org/0000-0001-7173-8908 (2021) Epitranscriptomic modification of cellular transcripts regulates KSHV lytic reactivation. PhD thesis, University of Leeds.

Milonaityte, Dovile ORCID: https://orcid.org/0000-0003-1596-5721 (2021) Characterisation of the interaction between FGFR2/EGL-15 and CRKL/CED-2. PhD thesis, University of Leeds.

Mitchell, Joanna Beth ORCID: https://orcid.org/0000-0002-2421-1449 (2021) Vascular endothelial growth factor inhibitors in the treatment of abnormal angiogenesis. PhD thesis, University of Leeds.

Mohamad, Merianne (2021) Towards an improved understanding of antibiotic resistance in the staphylococci, with an emphasis on characterising novel genetic determinants of resistance. PhD thesis, University of Leeds.

Morgan, Holly Elizabeth (2021) Diverse approaches to efficient sortase-mediated protein modification. PhD thesis, University of Leeds.

Moul, Sophie Louise ORCID: https://orcid.org/0000-0001-6084-9522 (2021) Understanding and Exploiting Peroxisomal Import Mechanisms. PhD thesis, University of Leeds.

Murphy, James Christopher ORCID: https://orcid.org/0000-0003-2702-9463 (2021) Does KSHV induce virus specific specialised ribosomes during infection? PhD thesis, University of Leeds.

N

Nicholson, David ORCID: https://orcid.org/0000-0001-5404-8251 (2021) Structural insights into ribosomes from pathogenic bacteria and their complexes with antibiotics and antibiotic-resistance ABC-F proteins. PhD thesis, University of Leeds.

P

Pickard, Megan Victoria (2021) Analysis of alpha-synuclein amyloid fibrils and their effects on the cellular proteome. MSc by research thesis, University of Leeds.

Prosser, Oliver Daniel (2021) Targeting functional RNA structures within the genomes of Chikungunya virus and Zika virus. PhD thesis, University of Leeds.

R

Richardson, Louise (2021) The role of satellite cells in skeletal muscle plasticity. PhD thesis, University of Leeds.

S

Saunders, Sophie Emma ORCID: https://orcid.org/0000-0002-3295-4453 (2021) Generation of Affimer proteins to study the role of Son of sevenless in oncogenic RAS signalling. PhD thesis, University of Leeds.

Shaw, Amelia Briony ORCID: https://orcid.org/0000-0002-6945-6124 (2021) Development of Molecular Tools for the Investigation of Arenavirus Spike Architecture. PhD thesis, University of Leeds.

Stainthorp, Amy Kate ORCID: https://orcid.org/0000-0001-9561-0095 (2021) Direct interaction between GRB2 and AGO2 regulates microRNA expression. PhD thesis, University of Leeds.

T

Timmis, Alex James (2021) Structure-function relationship of the Patched family of proteins. PhD thesis, University of Leeds.

Trask, Luke Antony ORCID: https://orcid.org/0000-0002-5538-3462 (2021) Probing the functions of Nek family kinases using chemical inhibition: towards the development of potent and selective inhibitors of Nek7. PhD thesis, University of Leeds.

Tsagakis, Ioannis ORCID: https://orcid.org/0000-0002-5136-9188 (2021) Dissecting the molecular mechanisms of lncRNA function in X chromosome inactivation across mammalian gestation evolution. PhD thesis, University of Leeds.

W

Walby, Samuel Jonathan (2021) Optimisation of the ONNV reverse genetic system. MSc by research thesis, University of Leeds.

Wright, Alexander James (2021) From Microscale Network Topology to Macroscale Mechanics of Folded protein Hydrogels. PhD thesis, University of Leeds.