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An investigation into pyocyanin-triggered carbon monoxide-releasing molecules

Steen, Rachel (2016) An investigation into pyocyanin-triggered carbon monoxide-releasing molecules. MSc by research thesis, University of York.

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Abstract

Pseudomonas aeruginosa (P. aeruginosa) infection is the most common cause of death amongst Cystic Fibrosis patients. Its virulence factor pyocyanin is of interest as a redox-active compound and has been investigated herein. Carbon-monoxide-releasing molecules have been developed in recent years to deliver carbon monoxide (CO), a known antimicrobial, safely and specifically to where it is required. Pyocyanin has been identified as a potential target to trigger CO-release as it is produced almost exclusively by P. aeruginosa.

Item Type: Thesis (MSc by research)
Academic Units: The University of York > Chemistry (York)
Depositing User: Miss Rachel Steen
Date Deposited: 06 Jun 2017 10:46
Last Modified: 06 Jun 2017 10:46
URI: http://etheses.whiterose.ac.uk/id/eprint/17378

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