White Rose University Consortium logo
University of Leeds logo University of Sheffield logo York University logo

Modulation of the Mitogen Activated Protein Kinase Pathway Spatiotemporal Signalling Components: Influence on Pathway Activation Behaviour Using an Agent Based Model

Shuaib, Aban (2016) Modulation of the Mitogen Activated Protein Kinase Pathway Spatiotemporal Signalling Components: Influence on Pathway Activation Behaviour Using an Agent Based Model. PhD thesis, University of Sheffield.

[img] Text (Full Thesis)
Sep19-16_AbanShauib_Thesis-Merged.pdf
Available under License Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales.

Download (11Mb)

Abstract

The subtleties of how the Mitogen Activated Protein Kinase works (MAPK) biochemical signalling pathway works, its emergent oscillatory behaviour and sensitivity is explained though an analysis of a computational agent based model that takes into account the distribution of the MAPK cascade components into multiple compartments

Item Type: Thesis (PhD)
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield)
The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Medicine (Sheffield)
Identification Number/EthosID: uk.bl.ethos.698288
Depositing User: Mr Aban Shuaib
Date Deposited: 25 Nov 2016 14:49
Last Modified: 25 Sep 2019 20:02
URI: http://etheses.whiterose.ac.uk/id/eprint/14404

You do not need to contact us to get a copy of this thesis. Please use the 'Download' link(s) above to get a copy.
You can contact us about this thesis. If you need to make a general enquiry, please see the Contact us page.

Actions (repository staff only: login required)