Dissecting the molecular mechanisms of lncRNA function in X chromosome inactivation across mammalian gestation evolution

Tsagakis, Ioannis ORCID: 0000-0002-5136-9188 (2021) Dissecting the molecular mechanisms of lncRNA function in X chromosome inactivation across mammalian gestation evolution. PhD thesis, University of Leeds.

Abstract

Metadata

Keywords: XIST, XCI, dosage compensation, lncRNA, lncRNA-protein co-evolution, lncRNA coevolution, RNA-binding protein, RNA-protein interaction, RBP, co-evolution, reproduction, placental mammal, Spen, Hnrnpk, Ciz1, Rbm15, Wtap, MATR3, RALYL, YY1, hnRNPU, TOP1, human, cow, mouse, bovine XIST, CodeML, RNA pulldown, RIP, TMT-MS
Awarding institution: University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds)
The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biology (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > Leeds Institute of Genetics, Health and Therapeutics (LIGHT)
The University of Leeds > Faculty of Biological Sciences (Leeds) > Institute for Molecular and Cellular Biology (Leeds)
Depositing User: Mr Ioannis Tsagakis
Date Deposited: 08 Jul 2022 14:00
Last Modified: 08 Jul 2022 14:00

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