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Clostridium difficile and its toxins

Hafiz, Saleem (1974) Clostridium difficile and its toxins. PhD thesis, University of Leeds.

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Abstract

An investigation of Clostridium difficile has shown : 1. that the organism is resistant to cresols and phenolq and may be grown from material grossly contaminated with other organisms by culture in media containing these substances; strains isolated before this method was evised are also resistant to cresols and phenol; 2. that the organism divides into four daughter cells; 3. that each strain examined has a different strain specific agglutinogen, and that the strains are otherwise antigenically complex; 4. that the sugar reactions are fairly consistent 5. that gelatin is liquefied by all available strains in three weeks; and that apart from this there is no proteolytic activity 6. that the hyaluronidase produced by all strains is antigenically uniform? and so is the lethal toxin; 7. and that the 'haemolysin' is almost certainly complex.

Item Type: Thesis (PhD)
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
Depositing User: Ethos Import
Date Deposited: 19 Jul 2010 10:54
Last Modified: 06 Mar 2014 16:54
URI: http://etheses.whiterose.ac.uk/id/eprint/972

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