Moody, Catherine Laura (2012) Improved Routes to Unsaturated Ketones and Heterocycles. PhD thesis, University of York.
Available under License Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 UK: England & Wales.
The work herein comprises two distinct projects: the first involves the construction of allylic ketones and enones directly from primary alcohols, using a novel one-pot procedure. Following development of this methodology, its application to the synthesis of indolizidine alkaloid elaeokanidine A was investigated. The second research area concerns the development of a copper(II)-catalysed radical cyclisation reaction to form spirocyclic oxindoles directly from linear anilides, along with subsequent preliminary studies towards to the synthesis of spirotryprostatin A.
|Item Type:||Thesis (PhD)|
|Keywords:||one-pot reaction, enone, indolizidine alkaloid, spirooxindole, spirotryprostatin A|
|Academic Units:||The University of York > Chemistry (York)|
|Depositing User:||Miss Catherine Laura Moody|
|Date Deposited:||29 May 2012 12:37|
|Last Modified:||08 Sep 2016 12:21|