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Synthesis of Substituted Azepanes and Piperidines Using Organolithium Chemistry

AEYAD, TAHANI (2018) Synthesis of Substituted Azepanes and Piperidines Using Organolithium Chemistry. PhD thesis, University of Sheffield.

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α-Amino-organolithium compounds represent an important class of intermediates due to their excellent nucleophilic reactivity and importance in synthetic organic chemistry. This thesis describes some novel aspects of the n-BuLi mediated lithiation‒substitution of N-Boc heterocycles, including N-Boc-2-substituted azepane, benzazepine and piperidine derivatives.

Item Type: Thesis (PhD)
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > Chemistry (Sheffield)
Depositing User: Miss TAHANI AEYAD
Date Deposited: 25 Jun 2018 08:25
Last Modified: 25 Jun 2018 08:25
URI: http://etheses.whiterose.ac.uk/id/eprint/20712

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