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Investigation of blood flow in the superior mesenteric artery and its potential influence on atheroma and gut ischaemia.

Jeays, Adam D (2006) Investigation of blood flow in the superior mesenteric artery and its potential influence on atheroma and gut ischaemia. PhD thesis, University of Sheffield.

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Abstract

Atherosclerosis is the underlying process in coronary heart disease leading to myocardial infarction, and in arterial damage leading to cerebrovascular accidents. It accounts for almost 50% of deaths in the western world. Atherosclerosis is characterised by the presence of fibro-lipid plaques (atheroma) within the vessel wall. Whilst the initiation and progression of atheroma are not fully understood, it is generally accepted that the time-varying haemodynamic wall shear stress (WSS) that the vessel wall is exposed to is important in determining the likelihood of development of an atherosclerotic plaque The superior mesenteric artery (SMA) is the major blood vessel feeding the small intestine; compared to other vessels of similar size, it is largely spared the effects of atherosclerosis.

Item Type: Thesis (PhD)
Academic Units: The University of Sheffield > Faculty of Science (Sheffield)
Other academic unit: epartment of Medical Physics and Clinical Engineering
Identification Number/EthosID: uk.bl.ethos.602393
Depositing User: EThOS Import Sheffield
Date Deposited: 25 Nov 2016 15:44
Last Modified: 25 Nov 2016 15:44
URI: http://etheses.whiterose.ac.uk/id/eprint/14700

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