Biophysical and structural characterisation of Protein-Protein interactions, HIF-1α/p300 and eIF4E/eIF4G to inform inhibitor rational design.

Kyle, Hannah Frances (2015) Biophysical and structural characterisation of Protein-Protein interactions, HIF-1α/p300 and eIF4E/eIF4G to inform inhibitor rational design. PhD thesis, University of Leeds.

Abstract

Metadata

Supervisors: Edwards, Thomas A and Wilson, Andrew J and Nelson, Adam N
Keywords: p300, HIF-1 alpha, eIF4e, eIF4g, Protein-protein interaction, biophysical characterisation
Awarding institution: University of Leeds
Academic Units: The University of Leeds > Faculty of Maths and Physical Sciences (Leeds)
The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Chemistry (Leeds)
The University of Leeds > University of Leeds Research Centres and Institutes > Astbury Centre for Structural Molecular Biology (Leeds)
Identification Number/EthosID: uk.bl.ethos.669609
Depositing User: Miss Hannah Kyle
Date Deposited: 16 Nov 2015 12:59
Last Modified: 25 Mar 2021 16:45

Download

Final eThesis - complete (pdf)

Export

Statistics


You do not need to contact us to get a copy of this thesis. Please use the 'Download' link(s) above to get a copy.
You can contact us about this thesis. If you need to make a general enquiry, please see the Contact us page.