Investigating quantified biomarkers of skin barrier function & anti-inflammatory skin treatment using optical coherence tomography

Optical coherence tomography (OCT) is a novel, non-invasive tomographic imaging technique which generates cross-sectional images of the tissue with a resolution of a few micrometres. With a penetration depth of a few millimetres that matches the skin thickness, OCT has also been applied in dermatology to identify skin layers, components and assess cutaneous disease progressions. In this research, with a clinical focus of atopic dermatitis (AD), novel OCT systems are used to investigate quantified biomarkers of skin barrier function & anti-inflammatory skin treatment for AD.