Duan, Mengqiu (2025) Investigating quantified biomarkers of skin barrier function & anti-inflammatory skin treatment using optical coherence tomography. PhD thesis, University of Sheffield.
Abstract
Optical coherence tomography (OCT) is a novel, non-invasive tomographic imaging technique which generates cross-sectional images of the tissue with a resolution of a few micrometres. With a penetration depth of a few millimetres that matches the skin thickness, OCT has also been applied in dermatology to identify skin layers, components and assess cutaneous disease progressions. In this research, with a clinical focus of atopic dermatitis (AD), novel OCT systems are used to investigate quantified biomarkers of skin barrier function & anti-inflammatory skin treatment for AD.
Metadata
Supervisors: | Matcher, Stephen |
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Related URLs: | |
Keywords: | Optical coherence tomography; visible-light optical coherence tomography; polarisation-sensitive optical coherence tomography; atopic dermatitis; eczema; skin biomarkers; skin barrier biomarkers; stratum corneum thickness; stratum corneum hydration; |
Awarding institution: | University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Electronic and Electrical Engineering (Sheffield) |
Depositing User: | Dr Mengqiu Duan |
Date Deposited: | 01 Jul 2025 14:28 |
Last Modified: | 01 Jul 2025 14:28 |
Open Archives Initiative ID (OAI ID): | oai:etheses.whiterose.ac.uk:36945 |
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