Faulkner, Lucy (2019) Raman spectroscopy as a diagnostic method for prostate cancer cell lines on a graphene substrate. MSc by research thesis, University of York.
Abstract
Raman Spectroscopy is a technique that can characterize samples using a non-invasive, label-free method. It has revolutionized the scientic research field identifying everything from pharmaceuticals, geology, and even biological applications. These biological applications include a deeper understanding of bone structure, drug and cell interactions and even advancements in the field of cancer diagnostics. This thesis uses this pioneering
technique to first characterise graphene sheets that have been obtained through chemical vapour desposition. Raman interactions can achieve a fingerprint signal, allowing a greater understanding of graphene's defects and composition. Using the peak's locations, full width at half maximum and intensity ratios will allow a comparison to literature, and lead to an in-depth understanding of the quality of graphene. Secondly, characterisation
of the prostate cancer cell line P4E6 will be completed. Various statistical analyses are performed to understand the prostate cell line's interactions with graphene
and the potential biological applications of graphene.
Metadata
Supervisors: | Hancock, Y |
---|---|
Awarding institution: | University of York |
Academic Units: | The University of York > School of Physics, Engineering and Technology (York) |
Academic unit: | Physics |
Depositing User: | Ms Lucy Faulkner |
Date Deposited: | 26 Jun 2020 23:55 |
Last Modified: | 26 Jun 2020 23:55 |
Open Archives Initiative ID (OAI ID): | oai:etheses.whiterose.ac.uk:26950 |
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