Synthesis of Diblock Copolymer Nanoparticles via Polymerisation-Induced Self-Assembly

Reversible addition-fragmentation chain transfer (RAFT) polymerisation has been used to synthesise a range of amphiphilic diblock copolymers. These diblock copolymers undergo polymerisation-induced self-assembly (PISA) to form spherical, worm-like or vesicular nano-objects, depending on the target diblock composition and the reaction conditions. These diblock copolymers are analysed by a variety of techniques including NMR, GPC, DLS and TEM.