Understanding the mechanics of myosin 5a through computational modelling and cryo-EM

Gravett, Molly Sarah Collins ORCID: 0000-0001-8351-7176 (2022) Understanding the mechanics of myosin 5a through computational modelling and cryo-EM. PhD thesis, University of Leeds.

Abstract

Metadata

Supervisors: Harris, Sarah and Muench, Stephen and Peckham, Michelle
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Keywords: motor protein, myosin, actin, modelling, cryoEM, cryo-EM, cryo-electron microscopy, molecular dynamics, biophysics, coarse-grained modelling, bending stiffness, myosin-5a, myosin-va, vesicular transport, molecular motors, walking, material parameters, material properties, flexibility, protein dynamics, hinges, strain, meshing, tetrahedral meshing, volumetric meshing, rod model, continuum, viscoelastic
Awarding institution: University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > Institute for Molecular and Cellular Biology (Leeds)
Depositing User: Miss Molly Sarah Collins Gravett
Date Deposited: 20 Apr 2023 13:03
Last Modified: 20 Apr 2023 13:03

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