Novel, Gram-negative targeting antimicrobial ruthenium complexes: in vitro and in vivo cytotoxicity and target identification.

Metadata

Supervisors:	James, Thomas and Simon, Foster
Related URLs:	Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria (Related publication) Mononuclear ruthenium(ii) theranostic complexes that function as broad-spectrum antimicrobials in therapeutically resistant pathogens through interaction with DNA (Related publication) Ruthenium based antimicrobial theranostics – using nanoscopy to identify therapeutic targets and resistance mechanisms in Staphylococcus aureus (Related publication) ranscriptomic Analysis of the Activity and Mechanism of Action of a Ruthenium(II)-Based Antimicrobial That Induces Minimal Evolution of Pathogen Resistance (Related publication) Triazole-based osmium(ii) complexes displaying red/near-IR luminescence: antimicrobial activity and super-resolution imaging (Related publication)
Keywords:	antimicrobial, antimicrobial resistance, bacteria, pathogen, infectious disease, ruthenium polypyridyl, metals in medicine
Awarding institution:	University of Sheffield
Academic Units:	The University of Sheffield > Faculty of Science (Sheffield) > Chemistry (Sheffield) The University of Sheffield > Faculty of Science (Sheffield) > Molecular Biology and Biotechnology (Sheffield)
Depositing User:	Miss Kirsty Smitten
Date Deposited:	08 Apr 2022 14:43
Last Modified:	08 Apr 2022 14:43

Embargoed until: 8 April 2027

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