Rapid induction of the unfolded protein response and apoptosis by synthetic oestrogen mimic TTC-352 and naturally-occurring oestrogen oestetrol for the treatment of endocrine-resistant breast cancer

Abderrahman, Balkees ORCID: https://orcid.org/0000-0001-9056-3453 (2020) Rapid induction of the unfolded protein response and apoptosis by synthetic oestrogen mimic TTC-352 and naturally-occurring oestrogen oestetrol for the treatment of endocrine-resistant breast cancer. PhD thesis, University of Leeds.

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Keywords: Breast cancer, oestrogen receptor, oestrogen-induced apoptosis, Selective Human oEstrogen Receptor Partial Agonists (ShERPAs), BMI-135, TTC-352, oestetrol, BPTPE, coactivators, endoplasmic reticulum stress, unfolded protein response, apoptosis
Awarding institution: University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
The University of Leeds > Faculty of Biological Sciences (Leeds) > Institute for Molecular and Cellular Biology (Leeds)
Identification Number/EthosID (e.g. uk.bl.ethos.123456): uk.bl.ethos.826698
Depositing User: Dr. Balkees Abderrahman
Date Deposited: 24 Mar 2021 15:34
Last Modified: 11 May 2021 09:53

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