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The relationship between insulin concentration and its effect on glucose utilization and metabolism in the isolated rat adipocyte

Brown, David (1974) The relationship between insulin concentration and its effect on glucose utilization and metabolism in the isolated rat adipocyte. PhD thesis, University of York.

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Abstract

It has been known for some considerable time that diabetes is associated with some loss of pancreatic function. In 1890 von Meering and Minkowsky showed that pancreatectomy caused diabetes in the dog and Schaffer (1895) suggested that the pancreatic control of carbohydrate metabolism might be mediated through an internal secretion of the islets of Langerhans. Studies involving pancreatic duct ligation and blockage subsequently confirmed the importance of the islet tissue in diabetes and Opie (1900-01) concluded from a study of pancreatic lesions that diabetes was always associated with a degeneration of the islet tissue.

Item Type: Thesis (PhD)
Academic Units: The University of York > Chemistry (York)
Identification Number/EthosID: uk.bl.ethos.480177
Depositing User: EThOS Import (York)
Date Deposited: 28 Sep 2015 09:22
Last Modified: 28 Sep 2015 09:22
URI: http://etheses.whiterose.ac.uk/id/eprint/9937

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